I started with 9mm and Unique powder. It's hard to get it wrong. 45 ACP is even easier, big fat case to work with. Plenty of data available on both. Start with a starting load out of a manual and work your way up.
Unique does not meter consistently in either Dillon or RCBS measures. Throw and weigh 20 consecutive charges and you'll see what I mean. WW231 is much better and HS6 is even better yet